Monthly Archives: August 2016

The Association between Hidradenitis Suppurativa and Crohn’s Disease: in Search of the Missing Pathogenic Link.


The Association between Hidradenitis Suppurativa and Crohn’s Disease: in Search of the Missing Pathogenic Link.

J Invest Dermatol. 2016 Sep;136(9):1747-8

Authors: van der Zee HH, Horvath B, Jemec GB, Prens EP

Abstract
Hidradenitis suppurativa is a chronic, autoinflammatory skin disease. Shalom et al. demonstrate in a large cross-sectional study an association between Crohn’s disease and hidradenitis suppurativa, but not with ulcerative colitis. This association supports the hypothesis that a similar pathogenic mechanism contributes to both diseases, providing new possibilities for functional studies and therapy development.

PMID: 27542293 [PubMed – in process]

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Posted in J Invest Dermatol | Comments Off on The Association between Hidradenitis Suppurativa and Crohn’s Disease: in Search of the Missing Pathogenic Link.

Hidradenitis suppurativa: A disease of infundibular epidermis, rather than pilosebaceous units?


Hidradenitis suppurativa: A disease of infundibular epidermis, rather than pilosebaceous units?

Br J Dermatol. 2016 Aug 20;

Authors: Janse IC, Blok JL, Diercks GF, Horváth B, Jonkman MF

Abstract
although the exact pathogenesis of hidradenitis suppurativa (HS) is unknown, it is established that it is primarily an infundibulitis.(1,2) We consider infundibulum as epidermis and not as hair follicle according to Ackerman, as the type of epithelial tissue of infundibular epidermis is indistinguishable from that of interfollicular epidermis.(1) This article is protected by copyright. All rights reserved.

PMID: 27542326 [PubMed – as supplied by publisher]

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Posted in Br J Dermatol | Comments Off on Hidradenitis suppurativa: A disease of infundibular epidermis, rather than pilosebaceous units?